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Light Reading

Newsletter for Life Sciences

Synergy Between 275 nm and 365 nm UV LEDs for Inactivation of RNase A

We have recently determined that a high irradiance 275 nm UV LED source inactivates RNase A at lower doses (joules/cm2) than lower irradiance source. Inactivation using 275 nm disrupts the disulfide bonds but does not directly affect the histidine or lysine amino acids known to be located in the enzyme’s active site. In this study, 365 nm UV LED....

More about the synergy between 275 nm and 365 nm >>

KeyPro™ KP100 Display Protocols

The KeyPro™ KP100 system provides high-intensity UV light in a benchtop instrument for decontamination and disinfection. The KeyPro KP100 irradiates microtiter plates to inactivate biological materials, such as DNA, RNA and enzymes like RNase A, using specific wavelengths of ultraviolet light. The instrument includes loading drawer access to the chamber with redundant interlock switches, allowing power to the LEDs when the drawer is fully closed. Both ultraviolet wavelengths are fully programmable by intensity and duration. The KeyPro KP100 has pre-loaded protocols for common microplates and glass slides, and users can create and save new protocols as needed.

Read More about the KeyPro >>

How LEDs Emit Light

Most people are familiar with Light Emitting Diodes (LEDs) in their everyday life, from car headlights to overhead lighting to mobile phones to street lighting. LEDs are on their way to becoming the dominant light source due to long lifetime, low energy consumption and almost infinite format capabilities. But how do they work?...


Solid State Detectors for Chromatography & Spectroscopy

Did you know?

Did you know that LEDs can be utilized for optical detection of most compounds of analytical interest, such as DNA, small molecules, and proteins? Accurate protein identification and quantification are critical steps in drug discovery and purity analysis. By looking at not just the absorbance of proteins at 220 nm, 260 nm and 280 nm, but also at the ratio of absorbance at those wavelengths, Phoseon is examining parameters for more detailed identification of proteins run in real-time, during either chromatography or spectrophotometry. Select your wavelength and see how you compare to other users.

Pin up to six wavelengths on the chart »

News & Events

Phoseon Technology Introduces High-Intensity UV LED Microplate Decontamination System

News & Events »

About the Author

Theresa L. Thompson, PhD joined Phoseon Technology in November 2016 as Application Scientist. Prior to Phoseon, Dr. Thompson was Chief Science Officer at Chimerochem, LLC and Vice President and Director of Research and Development at Dimera Incorporated before that. At Phoseon, Dr. Thompson is the lead Application Scientist focused on developing innovative LED technology for Life Sciences.

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