High-intensity UV LED Inactivation of Clostridium Difficile Spores

Phoseon Presents at SPIE BIOS Conference Sessions

High-intensity UV LED 275nm alone and 275nm+365nm combination, wavelengths targeted to protein disulfide functional groups, drive a greater than 5 log (5.79 log) CFU reduction of Clostridium difficile spores on a surface in less than 30 seconds. This is consistent with our results showing synergism between 275nm and 365nm high-intensity UV LED when irreversibly inactivating RNase A. Targeting protein stabilization and functional groups represents a new approach to spore inactivation.


Session 8: UV irradiation, Photothermal Therapy and Miscellaneous
High-intensity UV LED inactivation of Clostridium difficile spores
Paper 10863-39
Tuesday 5 February 2019
Time: 4:20 PM - 4:35 PM
Location: Room 70 (South Lower Mezzanine)
Author(s): Theresa Thompson, Jay Pasquantonio, Phoseon Technology, Inc.