Proteins within tissue and cells fluoresce when excited by UV light. Normal and abnormal cells respond differently due to underlying structural characteristics. This response can aid in differentiating tissue with real-time imaging or spectroscopy.
Exogenous dyes and markers are quite useful for visualizing different tissues in the body, but the workflow for delivering such compounds to the target areas can present a challenge. With a tailored light source and imaging system, endogenous fluorophores can be used for the same procedures for a smoother workflow with less time and cost.